SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 19 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Choline (from 630 mg Choline Bitartrate)
250 mg
45%
Inositol
250 mg
†
Top Medical Research Studies
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
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Most Useful Reviews
9.5
Liver function support
I've used this product for ten years following a scan revealing fatty layers in my liver, an early indication of severe liver disease. After extensive research, I discovered that choline bitartrate and inositol both help diminish fatty liver deposits. I continued taking them while maintaining my regular lifestyle, and subsequent tests have shown excellent liver health.
Read More
9.5
Energy boost felt
Liver Support! It's great for my nervous system! I love complex preparations that solve multiple issues. A gastroenterologist recommended choline to restore liver function and prevent stone formation. I needed this support, as I don’t eat the healthiest diet. Moreover, it has a mild impact on my nervous system. Inositol helps regulate blood sugar, crucial as insulin resistance risk rises with age. Since taking this, the heaviness in my right side has dissipated, and I feel lighter, calm, and energetic. I'm relieved that I made a good choice.
Read More
9.5
ALT levels reduced
I purchased this drug to lower ALT in the blood, as inositol can restore damaged liver cells affected by antibiotics and fatty hepatosis. After a month of use, I had a blood test revealing my ALT dropped from 120 to 45, which is nearly within the normal range.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 19 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Liver function support
I've used this product for ten years following a scan revealing fatty layers in my liver, an early indication of severe liver disease. After extensive research, I discovered that choline bitartrate and inositol both help diminish fatty liver deposits. I continued taking them while maintaining my regular lifestyle, and subsequent tests have shown excellent liver health.
Read More
9.5
Energy boost felt
Liver Support! It's great for my nervous system! I love complex preparations that solve multiple issues. A gastroenterologist recommended choline to restore liver function and prevent stone formation. I needed this support, as I don’t eat the healthiest diet. Moreover, it has a mild impact on my nervous system. Inositol helps regulate blood sugar, crucial as insulin resistance risk rises with age. Since taking this, the heaviness in my right side has dissipated, and I feel lighter, calm, and energetic. I'm relieved that I made a good choice.
Read More
9.5
ALT levels reduced
I purchased this drug to lower ALT in the blood, as inositol can restore damaged liver cells affected by antibiotics and fatty hepatosis. After a month of use, I had a blood test revealing my ALT dropped from 120 to 45, which is nearly within the normal range.
8.8
Calming effect
After nearly three months of consistent intake, I've had no gastrointestinal side effects. My experience with choline has been positive; it induces a calming sensation that eases my stress while helping regulate bodily functions effectively. I've noticed improvements in my body's natural cycles without adverse effects, making it a beneficial supplement.
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8
Improved health
I completed my course, primarily for the emulsifying action of choline, which helps discharge triglycerides from blood vessels. I noticed better clarity in thought, and it has become an essential supplement for managing my saliva and improving visibility during depressive episodes. I'm taking it with my husband, who has also felt the benefits.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
